CBD may have the potential to alter the effects of other medications, potentially leading to an increased risk of side effects or a decrease in the effectiveness of the medication. It is difficult to predict how CBD will interact with other drugs, but it is important to consult a doctor before taking CBD oil if you are taking any of the substances listed below. Research on CBD oil for migraine is limited, but some evidence suggests that it may help reduce chronic or acute pain. More research is needed to understand the severity of interactions between different drugs and CBD, and to develop recommendations for taking them together.
We mentioned earlier that NSAIDs interact with CBD, which may raise concerns about possible negative interactions between CBD oil and ibuprofen. This inhibitory effect on CYP450 enzymes depends mainly on the amount of CBD a person takes, their unique physiology and the type of CBD consumed (e.g., as well as on the more traditional means of consuming cannabis, such as smoking). CBD oil is becoming increasingly popular due to its potential health benefits, but it is important to consider how it may interact with certain medications used to treat similar symptoms. CBD inhibits CYP3A4, meaning that taking CBD and sertraline at the same time could be dangerous.